Certified Nephrology Nurse Certification (CNN) Practice Exam

Acetaminophen is not commonly associated with interstitial nephritis, which is an inflammation of the kidney interstitium often caused by adverse reactions to medications. While nonsteroidal anti-inflammatory drugs (NSAIDs) and certain antibiotics like cephalosporins and sulfonamides are more frequently linked to this condition, acetaminophen is generally considered safe for the kidneys when used at recommended doses. Cocaine can cause renal injury through several mechanisms, including vasoconstriction and the potential for acute kidney injury, further contributing to kidney-related issues. Cephalosporins and sulfonamides have been well-documented in medical literature as medications that can induce interstitial nephritis due to hypersensitivity reactions. In contrast, acetaminophen, when taken appropriately, does not carry the same risk for causing interstitial nephritis, making it the correct choice in this context.